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Rachel Delorme

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Laboratoire de Physique Subatomique et Cosmologie, Grenoble, France


Research topics

I am a permanent CNRS researcher of the National Institute of Nuclear and Particle Physics since 2016. I have obtained the qualification of Radiological and Medical Physics in 2009 and a doctorate in Physics in 2013. All of my research activities have been focused on the development, optimization and understanding of innovative radiotherapies (RT), with a large part of it implying Monte Carlo simulations. During my successive research projects, I contributed to the understanding of targeted therapy efficiency, as in RT enhanced by metallic nanoparticles and Boron Neutron Capture Therapy (BNCT), by means of macro, micro and nano-dosimetric simulations. I also performed dosimetry and numerical studies for new irradiation-mode radiotherapy, as in Flash therapy, Very High Energy Electron (VHEE) RT and spatially fractionated RT (SFRT). My main projects in the future as GATE user and developer, are related to the improvement of biological dose prediction and characterization of microdosimetric quantities, by means of Gate/Geant4-DNA simulations coupled with biophysical models (MKM or NanOx), applied to VHEE RT, SFRT approaches and targeted therapies implying low-energy ions (BNCT and alpha targeted therapy).